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The gelling agent used, Carbomer 940, is a gel-forming agent that is safe to use because it is non-toxic and non-irritating, while the humectants used are glycerin and propylene glycol. The composition of the gelling agent must be considered so as to produce preparations that have good stability and physical properties. The physical and stability of the gel are determined by the gelling agent and humectant used. The high water content in the gel base can cause hydration of the stratum corneum so that it will facilitate drug penetration through the skin. The use of spoon leaves as an anti-inflammatory can be facilitated by formulating it in a gel preparation.
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The gel is able to provide a cool feeling on the skin so that it feels comfortable when applied to the intended area and the preparation is easy to dry to form a film that is easily washed off with water. The advantages of the maceration method are that the tools used are simple and low cost. The purpose of remaceration is to get a lot of active substances because by using a new solvent the absorption is stronger to attract the active substances in the leaves. The extraction method used is the maceration method by modifying the remaceration. The selection of the extraction method is very important because the extraction results will reflect the success rate of the method used. Extraction is the process of separating compounds in solution based on differences in their solubility.

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The chemical content of aucubin is obtained through the extraction process. The chemical content which has anti-inflammatory properties, namely aucubin. Sendok Leaf Extract (Plantago major L.) has several pharmacological activities, one of which is anti-inflammatory. Sendok leaves (Plantago major L.) are very easy to grow and categorized as weeds, but after commercialization efforts for herbal, many harvests are carried out from nature, even in some areas they have begun to be cultivated. This site does not host pdf, DOC files all document are the property of their respective owners.The use of traditional plants as medicine is the main choice for some Indonesian people, this is because drugs derived from plants have a cheaper price, are easier to obtain and have low side effects.
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